蔡进辉个人简介

基本信息

姓名：蔡进辉

出生年月：1992.10

学位：博士

职称：校聘教授

研究领域（方向）：（1）不对称催化； （2）廉价金属参与的自由基化学； （3）[2+2+n]环加成反应 （4）电催化以及硒化学

联系方式：

邮箱：jinhuicai@usc.edu.cn；15898595191@163.com

个人简介

蔡进辉，男，1992年生，湖南益阳人，博士，校聘教授，硕士生导师。现主持国家自然科学基金青年项目、湖南省自然科学青年项目、南华大学博士科研启动基金等，参与多项面上项目；目前在Chem、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、ACS Catalysis、Chem Catalysis、Org. Lett.、Green Chem.、Adv. Syn. Catal.、J. Org. Chem.、Org. Biomol. Chem.、Asian. J. Org. Chem.、Synthesis、RSC Adv.等期刊上发表论文22篇，其中以通讯作者、第一作者、导师第一本人第二发表论文17篇；授权专利2项。

教育经历

2017/09-2020/06 武汉大学，化学与分子科学学院，博士，导师：刘文博

2014/09-2017/06 湘潭大学，化学学院，硕士，导师：邓国军、黄华文

2013/09-2014/05 中科院化学所，分子识别与功能实验室，联培本科生，导师：王从洋

2010/09-2014/06 湘潭大学，化学学院，学士

科研、学术与访学工作经历

1. 2021/06-现今，南华大学，化学化工学院，校聘教授

2. 2020/07-2021/06，浙江大学，化学系，博士后，合作导师：史炳锋

主持或参加科研项目（课题）情况

2024.01—2026.12 基于光诱导钴催化不对称[2+2+2]环加成反应合成新型手性氮杂螺烯化合物及其性能研究，国家自然科学基金（22301128），主持，经费30万；

2022.01—2024.12 基于钴催化1,6-烯炔化合物和腈类化合物的不对称环化反应的研究，湖南省自然科学基金（2022JJ40353），主持，经费5万元；

2021.06—至今 廉价金属钴催化1,6-烯炔化合物的不对称碳环化反应的研究，南华大学博士启动经费，主持，经费30万元。

主要论文：

1.Kaili Cen,^# Zhouting Zeng,^# Wangzhen Shen,^# Yuting Feng, Pingzhi Yan, Jiahao Wei, Qian Hou, Junjie Fu, Xiaotong Xia, and Jinhui Cai*, Cu-Catalyzed C(sp²)-H Bond Aminosulfonylation of Maleimides. Adv. Synth. Catal. 2023, 365, 2530–2535. (^#共同第一作者)

2.Kaili Cen,^# Jiahao Wei(本科生),^# Yuan Liu(本科生),^# Zhixuan Tan, Xinye Wang, Dahan Wang,* Wei-Min He,* and Jinhui Cai*, Electrochemical Selenylation of Alkynyl Aryl Ketones: Efficient Synthesis of 3-Selenylated Chromones under Catalyst- and Chemical-Oxidant-Free Conditions. Eur. J. Org. Chem. 2023, 26, e202300968. (^#共同第一作者)

3.Kaili Cen,^# Jiahao Wei(本科生),^# Yuting Feng(本科生),^# Yuan Liu, Xinye Wang, Yangyu Liu, Yalin Yin, Junhong Yu, Dahan Wang* and Jinhui Cai*, Synthesis of fused 3-trifluoromethyl-1,2,4-triazoles via base-promoted [3+2] cycloaddition of nitrile imines and 1H-benzo[d]imidazole-2-thiols, Org. Biomol. Chem. 2023, 21, 7095–7099. (^#共同第一作者)

4.Dahan Wang*, Xiaoyuan Wan, Yazheng Zhou, Jinbing Liu, Jinhui Cai*, Guo-Jun Deng*, Facile Synthesis of Fully Substituted 1,2,4-Triazoles via [3+2] Cycloaddition of Nitrileimines with Amidine under Transition Metal-Free Conditions. Asian J. Org. Chem. 2023, 12, e202200674.

5.Jinhui Cai*, Kaili Cen, Wangzhen Shen, Li-Gang Bai, Wen-Bo Liu,* [2+2+2] Cycloaddition of nitriles to enantioenriched and highly substituted pyridines. Chem Catal. 2022, 2, 2889.

6.Kaili Cen^#, Muhammad Usman^#, Wangzhen Shen, Meijing Liu, Rong Yang, Jinhui Cai* A review for the assembly of multi-substituted pyridines via Co-catalyzed [2+2+2] cycloaddition with nitriles. Org. Biomol. Chem. 2022, 20, 7391 − 7404.

7.Jinhui Cai^#, Li-Gang Bai^#, Yiliang Zhang, Zhen-Kai Wang, Fei Yao, Jin-Huang Peng, Wei Yan, Yan Wang, Chao Zheng, Wen-Bo Liu, Nickel-Catalyzed Enantioselective [2+2+2] Cycloaddition of Malononitriles and Alkynes. Chem 2021, 7, 799 – 811.

8.Huawen Huang*, Jinhui Cai, Xiaochen Ji, Fuhong Xiao, Ya Chen, Guo-Jun Deng*, Internal Oxidant-Triggered Aerobic Oxygenation and Cyclization of Indoles under Copper Catalysis. Angew. Chem. Int. Ed. 2016, 55, 307 − 311. (导师第一，本人第二)

9.Qiang Wei^#, Jinhui Cai^#, Xu-Dong Hu, Jing Zhao, Hengjiang Cong, Chao Zheng, and Wen-Bo Liu, Enantioselective Access to γ-All-Carbon Quaternary Center-Containing Cyclohexnaones by Palladium-Catalyzed Desymmetrization. ACS Catal. 2020, 10, 216 – 224. (共一)

10.Jinhui Cai^#, Feifei Li^#, Guo-Jun Deng, Xiaochen Ji*, Huawen Huang*, The Cyclopropylimine Rearrangement/Povarov Reaction Cascade for the Assembly of Pyrrolo[3,2-c]quinoline Derivatives. Green Chem. 2016, 18, 3503 – 3506. (共一)

11.Jinhui Cai, Zhen-Kai Wang, Yun-Hao Zhang, Fei Yao, Xu-Dong Hu, and Wen-Bo Liu, Synthesis of Polysubstituted 2-Naphthols by Palladium-Catalyzed Intramolecular Arylation/Aromatization Cascade. Adv. Synth. Catal. 2020, 362, 1303 – 1308.

12.Jinhui Cai, Zhen-Kai Wang, Muhammad Usman, Zhi-Wu Lu, Xu-Dong Hu, and Wen-Bo Liu, Enantioselective Synthesis of βQuaternary Carbon-Containing Chromanes and 3,4-Dihydropyrans via Cu-Catalyzed Intramolecular C−O Bond Formation. Org. Lett. 2019, 21, 8852 – 8856.

13.Jinhui Cai, Qiang Wei, Xu-Dong Hu, Yan Zhang, Weishuang Li, Hengjiang Cong, Wei Liu, Wen-Bo Liu, Enantioselective Construction of Bridgehead Quaternary Carbon Containing Bicyclo[3.3.1]nonanes by Palladium-Catalyzed Desymmetric Arylation. Synthesis 2018, 50, 1661 – 1666.

14.Yujia Xia^#, Jinhui Cai ^#, Huawen Huang* and Guo-Jun Deng*, Synthesis of polysubstituted pyridines from oxime acetates using NH₄I as a dual-function promoter. Org. Biomol. Chem. 2018, 16, 124 − 129. (共一)

15.Huawen Huang*, Jinhui Cai, Hao Xie, Jing Tan, Feifei Li, and Guo-Jun Deng*, Transition-Metal-Free N−O Reduction of Oximes: A Modular Synthesis of Fluorinated Pyridines. Org. Lett. 2017, 19, 3743 − 3746. (导师第一，本人第二)

16.Huawen Huang*, Jinhui Cai, Lichang Tang, Zilong Wang, Feifei Li, Gu-Jun Deng*, Metal-Free Assembly of Polysubstituted Pyridines from Oximes and Acroleins. J. Org. Chem. 2016, 81, 1499 − 1505. (导师第一，本人第二)

17.Huawen Huang*, Jinhui Cai, Guo-Jun Deng*, O-Acyl Oximes: Versatile Building Blocks for N-heterocycle Formation in Recent Transition Metal Catalysis, Org. Biomol. Chem. 2016, 14, 1519 − 1530. (导师第一，本人第二)

18.Zhi-Wu Lu^#, Xu-Dong Hu^#, Hui Zhang, Xiao-Wen  Zhang, Jinhui Cai, Muhammad Usman, Hengjiang Cong, Wen-Bo Liu, Enantioselective Assembly of Cycloenones with a Nitrile-Containing All-Carbon Quaternary Center from Malononitriles Enabled by Ni-Catalysis. J. Am. Chem. Soc. 2020, 142, 7328 – 7333.

19.Huawen Huang,* Feifei Li, Zhenhua Xu, Jinhui Cai, Xiaochen Ji,* and Guo-Jun Deng, Base‐Promoted [3+2]‐Annulation of Oxime Esters and Aldehydes for Rapid Isoxazoline Formation. Adv. Synth. Catal. 2017, 359, 3102 – 3107.

20.Hao Xie, Jinhui Cai, Zilong Wang, Huawen Huang*, Guo-Jun Deng*, A Three-component Approach to 3,5-Diaryl-1,2,4-thiadiazoles under Transition-Metal-Free Conditions. Org. Lett. 2016, 18, 2196 – 2199.

21.Huamin Wang, Jinhui Cai, Huawen Huang, Guo-Jun Deng*, Palladium-catalyzed Phtha-lazinone Synthesis Using Paraformaldehyde as Carbon Source. Org. Lett. 2014, 16, 5324 – 5327.

22.Huawen Huang,* Lichang Tang, Jinhui Cai, and Guo-Jun Deng,* Mild and ambient annulations for pyrrole synthesis from amines and arylacetaldehydes. RSC Adv. 2016, 6, 7011 – 7014.

专利：

1.刘文博，蔡进辉，一种季碳中心的全取代吡啶化合物及其制备方法，中国专利，专利号：ZL202010507993.7。

2.黄华文，蔡进辉，谢艳军，邓国军，2,3a-二取代-3H–吡唑并[1,5-a]吲哚-4(3aH)-酮、衍生物及其合成方法，中国专利，专利号：ZL201510675567.3。

二、出版的著作（教材）及获奖

无